All Hotels and Inns

Audubon’s Hotel One of Missouri’s Longest Running Hotels At 9 North Main Street in downtown Ste. Genevieve, Audubon’s blends boutique hotel charm with restaurant excellence in a building that has anchored the town’s social scene since 1901. First opened as the City Hotel in 1904, this 120-year-old structure underwent complete renovation in 2018, transforming into seven contemporary luxury rooms, each with private bathroom. Current owners Brock and Megan Gibson—who also own Dannie’s Sports Tavern and The Beacon—purchased the establishment in fall 2024 from the Fallerts and Fergusons, inheriting what Brock calls “an absolute gem” and “a very important place in this town.” With a first-floor restaurant serving scratch-made French, Cajun, German, and Italian cuisine, a beer garden across the street, and an untapped basement cellar, Audubon’s delivers what one longtime visitor describes as “the best hotel in town…the location can’t be beat. All the important historic attractions and restaurants are within walking distance. A person can park, check in, and never get in your car again.” Palace Bar to Boutique Hotel: 120 Years of Downtown Vitality The property’s story begins in 1901 when Charles Petrequin purchased it for just over $2,000. By 1903, it housed the historically famous Palace Bar—a Read more…

Dr. Hertich House Built in 1850 as both residence and medical clinic for Dr. Charles Hertich, one of Ste. Genevieve’s first full-time physicians, this French Chateau-style building with distinctive mansard roof now serves as a heritage hotel blending historic elegance with modern luxury. Located at 99 North Main Street in the heart of downtown, Dr. Hertich House offers four three-room suites with king beds, gas fireplaces, and two-person jacuzzi tubs—plus Der Bierkeller, a unique basement apartment nestled within original 1801 stone foundation walls. Under new ownership by Dr. Sandra Hoffmann (herself a practicing physician at Ste. Genevieve County Memorial Hospital), the property continues the medical legacy while delivering what guests call “the ultimate in comfort.” As one anniversary couple raved: “My wife and I stayed in the Memories Suite and it was perfect. Extremely comfortable king bed, easy-to-use gas fireplace at the foot of the bed, and an awesome two-person jetted tub with complimentary bath salts. We had the stuffed french toast delivered to our suite the following morning—5 star service!” 1850 French Chateau Meets Heritage Hotel Dr. Charles Hertich purchased the property in 1850 for $1,800, when only the northern portion existed. The southern section came later. For decades, Read more…

Main Street Inn Bed & Breakfast – Where Art, History, and Vision Transform Hospitality in Sainte Geneviève Step through the doors of the Main Street Inn Bed & Breakfast and you immediately understand that your time here will be a curate experience. Originally built in 1882 as the Meyer Hotel, this three-story brick landmark has welcomed travelers to Sainte Geneviève for more than 140 years. But following an extensive year-long renovation, proprietors Susan O’Donnell and Patrick Fahey transformed this historic property into something extraordinary: a bed and breakfast where world-class art, meticulous attention to preservation, and genuine hospitality create an experience that aligns with what you’d expect in Missouri’s oldest city. The Main Street Inn stands as home, gallery and gathering place, historic structure and comfortable retreat. Here, you’re encourage to meander through the house and take inspiration in the work that went into its restoration and the nuance of its collection.  For those visitors that are looking to bring home fresh inspiration to their design sensibilities, this is the stay for you. This is lodging for people who appreciate art, value history, and seek accommodations with personality and purpose rather than generic hotel uniformity. An Unexpected Gallery in Missouri’s Read more…

Baetje Farms Lodging – Five Luxury Tiny Homes on a World-Renowned Goat Cheese Farm Where French Country Elegance Meets Missouri Countryside At 8932 Jackson School Road in Bloomsdale, just three miles off Interstate 55 at the entrance to Ste. Genevieve County’s wine country and directly across from Chateau Ste. Genevieve winery, Baetje Farms has created something genuinely unique: five luxury tiny homes where guests sleep steps away from the white Saanen goats whose milk becomes award-winning French-inspired artisan cheese—Bloomsdale (the flagship Super Gold World Cheese Awards winner inspired by Valencay), Miette (“small, sweet thing,” their most awarded honeymoon-perfect cheese), Coeur de la Crème (heart-shaped chèvre in multiple flavors), Vallée, and Amoureux—each tiny home named after a different Baetje cheese and designed with white planked oak floors, shiplap walls, white marble tiled bathrooms, floor-to-ceiling windows with flowing curtains, and French country chic décor honoring Ste. Genevieve County’s deep Francophone heritage. Accommodating up to 17 guests across all five homes (four romantic one-bedroom suites plus one stunning two-story Bloomsdale Suite sleeping nine with spiral staircase, double loft with four built-in queen bunk beds, floating bar, and outdoor fire pit), the tiny homes offer intimate escapes for couples, complete buyouts for wedding parties Read more…

21958 Highway 32 Ste. Geneviève, MO 63670 800-230-3734 Hometown Inn & Suites (formerly the Microtel) has 42 double queen rooms plus 6 suites. Meeting rooms are available. Tour groups, reunions, and weddings are welcome. Room reservations include free continental breakfast, local calls, high-speed internet, lobby computer, refrigerator, and a microwave. Read more…